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Nolvadex


Generic Name: tamoxifen (ta-MOX-i-fen)
Brand Name: Nolvadex


Nolvadex and Its Intake Instructions

When you hear about Nolvadex, you should know that this medicine is taken by patients to treat breast cancer and prevent it from spreading to other body parts. Besides, doctors prescribe it after radiation therapy and surgery to decrease a chance of this cancer type in high-risk profiles. Nolvadex functions by interfering with important estrogen effects in breast tissues, thus, blocking the growth of cancer. Sometimes, it can be used to stimulate ovulation, too.

Basic Guidelines on How to Use It

This medication can be taken orally with and without food once or twice a day according to the directions of your doctor. Standard daily doses are usually about 20 mg, but if you prefer to use the liquid form of this medicine, ensure that each dosage is measured carefully. Keep in mind that it must be based on a set of important factors, such as your personal response to this treatment. For those patients whose breast cancer spreads to other body areas, you may notice increased pain and such symptoms as new or increased tumors. The good news is that they disappear fast, but you should inform your doctor about them at once. For nursing and pregnant female patients, it’s not advisable to use Nolvadex, unless it’s clearly needed.

Uses and Drug Class

This medicine was approved by the FDA almost 20 years ago, but its precise mechanism of action is still unknown. There are suggestions that it binds and blocks the receptors of estrogen on cell surfaces, thus, preventing this hormone from activating them. Nowadays, you can find Nolvadex in the form of standard tablets and special oral solutions available in different doses. When it comes to stimulating ovulation, you need to take 5-40 mg two times a day for a few days. If you need to treat or prevent breast cancer, it’s necessary to take 20 mg for 5 years.

Possible Adverse Effects

Like other medications, Nolvadex may cause certain side effects, such as the following:

  • Sudden weight loss;
  • Hot flashes;
  • Vaginalbleeding and discharge;
  • Changes in menstrualperiods;
  • Dizziness and lightheadedness;
  • Nausea and vomiting;
  • Headaches;    
  • Fatigue and depression;
  • Coughing;
  • Fluidretention.

In very rare cases patients may experience serious side effects, such as:

  • Blood clots and vein thrombosis;
  • Certain abnormalities in liver tests, decreased red and white blood cells, etc.

Dangerous Drug Interactions

Make sure that you don’t combine the intake of Nolvadex with specific medications, including Femara, Arimidex and Coumadin if you don’t want to end up with increased blood thinning effects. Besides, it’s not advisable to combine this medicine with rifampin and Phenobarbitals.

In conclusion, there are certain warnings that should be considered before starting this treatment. If you develop any symptoms of blood clots or stroke, you need to see your doctor at once, and they include unexpected vision changes, difficulty breathing, swelling, slurred speech and others.

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